How Long Does Lion's Mane Stay in Your System? | Botanic Tonics

How Long Does Lion's Mane Stay in Your System? | Botanic Tonics

Reviewed by Jamal Bouie


Lion’s mane, or Hericium erinaceus, is an edible mushroom widely utilized throughout history and in traditional Chinese medicine for its medicinal properties. This ingredient has roots in Eastern treatments dating back hundreds of years, and today, many people still use it when seeking health benefits like improved brain function, oxidative stress reduction, and mental clarity.[1]

If you’ve been wanting to give this supplement a try, you may be wondering: how long does Lion’s Mane last? 

In this article, we’ll explain everything you need to know about this medicinal mushroom so you can understand lion’s mane thoroughly before experiencing it yourself. Read on to learn how long this mushroom stays in your system and what effects you can expect from it. 

How Long Does It Take For Lion’s Mane To Start Working?

Before you decide how to take lion’s mane, it’s important to understand how long it will take to take effect. Depending on which form you take lion’s mane in, the time you’ll need to wait to feel its effects set in will vary. Some people ingest the mushroom as a dried-up powder. Others cook it or make it into soups and teas. Still, others choose to eat the fresh mushroom completely raw. 

You can also drink lion’s mane extract as a kava tonic. If you ingest the ingredient through this medium, you may start to feel its effects after just 15-30 minutes. 

Taking lion’s mane in the form of a capsule pill can make this wait a little bit longer, with results generally being experienced approximately 30-45 minutes after consumption. 

When the desired effects do kick in, you can start to notice health benefits such as: 

  • Smoother, calmer socializing 
  • A clean energy boost
  • Enhanced mental clarity and ability to focus 
  • Improved relaxation 
  • Stimulated productivity 

Studies also suggest that taking lion’s mane can lead to increased brain cell growth, improved mental health through alleviating depression and anxiety, better gut health, and more.[2]

What Factors Affect How Long Lion’s Mane Stays In Your System?

Let’s tackle the big question: how long does lion's mane stay in your system? 

Although there is no one-size-fits-all answer to this question, keeping in mind a few key factors can help you determine a rough estimate of how long this supplement may linger in your system. The duration of the mushroom’s effect on your body will depend on:[3]

  • The amount you ingest
  • How often you take it 
  • How full your stomach is 

In addition, your unique body size, metabolism, health, and age will play a role in how long you feel the effects of lion’s mane. 

If you are brand new to the world of beneficial mushrooms, starting off with smaller, less frequent doses can be a smart way to get more comfortable consuming these active compounds. 

Does Lion’s Mane Show Up On A Drug Test?

The great thing about a supplement like lion’s mane is that it is not a psychedelic mushroom. So, like most mushroom types, it will not show up on standard drug tests at all.[4]

What Dosage of Lion’s Mane Is Recommended? 

There are many different ways to ingest lion’s mane, but it is generally recommended that consuming between 250-750 mg daily will give the best results.[5] No matter how you decide to take lion’s mane, it is imperative to follow the dosage recommendations provided by the manufacturer. 

Two popular methods of taking lion's mane include liquid extract and capsules. 

Our feel free tonic, for example, is a kava drink packed with all the benefits of lion’s mane, as well as other ancient herbs like: 

  • Kava root
  • Kola nut
  • Rhodiola

This medley of natural ingredients is believed to enhance relaxation and stimulate cognitive function. On average, the effects of this drink will last for 3-4 hours. Half a bottle constitutes one serving, and we do not recommend taking more than 2 servings per day. 

Try Lion’s Mane For Your Benefit With Botanic Tonics

When investing in supplements, it is important to only use trusted brands approved by rigorous scientific testing. This way, you can have a safe and enjoyable experience while reaping the benefits of ancient remedies like lion’s mane mushrooms. 

That’s where we can help. At Botanic Tonics, we’re committed to providing only the highest quality ingredients in our tonics and capsules. If you’re intending to use our products as a coffee alternative, or just want a beneficial boost to your daily routine, you can rely on our feel free drinks and feel free capsules.

Peruse our selection of plant-based products today. We manufacture in the USA and are fully committed to providing the highest quality products. 


  1. Live Naturally Magazine. Lion’s Mane: Benefits & How To Take It.
  2. healthline. 9 Health Benefits of Lion’s Mane Mushroom (Plus Side Effects).
  3. healthline. Will Mushrooms Show Up on a Drug Test?
  4. MedicalNewsToday. Shrooms and drug tests: What to know.
  5. Soma Analytics. Lion’s Mane Mushroom.

          About The Author

          Jamal Bouie Botanic Tonic

          Jamal Bouie

          Jamal Bouie is an accomplished professional with a Bachelor’s Degree in Chemistry from Lemoyne-Owen College in Memphis. Currently, he is pursuing his PhD in Biomedicine at Salus University. Jamal has worked in several industries; he began his career in pharmaceutical manufacturing and transitioned to the cannabis industry, where he specialized in analytical testing and manufacturing, playing a vital role in ensuring product safety and compliance. Now, Jamal has turned his attention to the dietary supplement field, combining his scientific acumen with his passion for health and wellness.

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